You don't need to have any 2D animation software to create a spinning preloader. If you use Photoshop, you're good to go.
In this video, I will show you how to create a spinning preloader using the timeline in Photoshop.
To create the additional preloaders at the end of the video, click here: http://2-minutedesign.com/post/cropped-faded-spinning-gif-preloaders-photoshop/